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Heart Health Guide

Obesity and Weight Loss

Obesity and Weight Loss

Key takeaway

Obesity is a chronic medical condition, not a lack of willpower. Here is how the new GLP-1 medications work, and what they can and cannot do on their own.

Obesity is a chronic medical condition, not simply a lack of willpower. When people lose weight, the body naturally fights back by increasing hunger and slowing metabolism, making it difficult to keep the weight off.

New medications called GLP-1 receptor agonists, such as semaglutide (Rybelsus, Ozempic, Wegovy) and tirzepatide (Mounjaro), help control appetite and support long-term weight loss by working on the body’s natural hunger signals. This shifts the paradigm of our approach.

Why Obesity Matters

Obesity increases the risk of many serious health conditions, including:

  • Heart disease, high blood pressure, and stroke
  • Type 2 diabetes
  • Fatty liver disease
  • Sleep apnea
  • Osteoarthritis
  • Several types of cancer

How GLP-1 Medications Work

These medications help by:

  • Reducing hunger and cravings
  • Helping you feel full sooner and for longer
  • Slowing stomach emptying
  • Improving blood sugar control and managing energy storage around internal organs

Benefits of Weight Loss

Studies show that losing 10% to 20% of body weight (with GLP-1 medications) can:

  • Lower the risk of heart attack, stroke and kidney dysfunction
  • Improve blood sugar levels
  • Reduce inflammation in the body
  • Improve sleep apnea
  • Reduce stress on joints and the liver

Long-Term Success

Because obesity is a chronic disease, weight often returns when treatment stops. For the best results, GLP-1 medications should be combined with:

  • A healthy, balanced diet
  • Regular physical activity
  • Adequate protein intake to maintain muscle mass
  • Self-discipline, especially when treatment stops

By treating the biological causes of weight gain, GLP-1 medications help people achieve meaningful weight loss and reduce the risk of obesity-related diseases.

Are GLP-1 medications safe?

All medications may have potential risk and side effects. GLP-1 medications are generally safe. Please enquire with your doctor to find out more.

Medical disclaimer

This guide is for general education only and is not a substitute for personalised medical advice. For concerns about your heart, please consult a cardiologist.

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